Selection-005

Parasite density and erythrocyte sedimentation rate on patients with uncomplicated tropical malaria in two puskesmas of west Lombok

  • Kadeq Novita Prajawanti Graduate School of Immunology, Postgraduate School, Universitas Airlangga, Surabaya
Keywords: Parasite Density, Erythrocytes Sedimentation Rate, Uncomplicated Malaria Tropica

Abstract

Malaria infections are often associated with the activation of coagulations and fibrinolytic systems. An increase number of fibrinogen levels in severe malaria, and the increased of fibrinogen also stimulated the increase of erythrocytes sedimentation rate. The aim of this study is to find out about the effects of high parasitemia to erythrocyte sedimentation rate in patients with uncomplicated tropical malaria. Sampel are collected using Purposive Samplings method. To determined the effect of parasite density to ESR levels (mm/h), the data were analyze using One Way Anova test (α=0,05). From 8 samples, 2 subjects (25%) has ++ (+2) densities with 35 and 46 mm/h; 3 subjects (37,5%) has +++ (+3) densities with 10, 65 and 70 mm/h; and also 3 other subjects (37,5%) has ++++ (+4) densities with 21, 44, and 70 mm/h. ANOVA test has shown that p value 0,949 >α, means that there is no effect about parasite density to ESR levels. ESR; erythrocytes sedimentation rate

Keyword:

Parasite Density, Erythrocytes Sedimentation Rate, Uncomplicated Malaria Tropica

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References

Laihand Ferdind J. (2011). Epidemiologi Malaria di Indonesia. Buletin Jendela Data dan Informasi Kesehatan. Jakarta: Pusat Data dan Informasi Kementerian Kesehatan RI.

Kurniasih, Yulvina & Mulyani, Reskiani. (2018). Gambaran Eritrosit Pada Sediaan Darah Tepi Pasien Malaria Di Puskesmas Sungai Pancur. J Endur. 3(2):226–31. DOI: http://doi.org/10.22216/jen.v3i2.1822

Arsin, Andi Arsunan. (2012). Malaria di Indonesia (Tinjauan Aspek Epidemiologi). Masagena Press: Makassar

Liwan, Armand Setiadi. (2015). Diagnosis dan Penatalaksanaan Malaria Tanpa Komplikasi pada Anak. 42(6):425–9.

Gomes, Andreia P., Vitorino, R.R., Costa, A. de P., Mendonca, E., Oliveria M.G., Siqueira-Batista, R. (2011). Severe Plasmodium falciparum malaria. Rev Bras Ter Intensiva. 23(3):358–69.

Chairland., Lestari, E., Mahode, A. A. (2011). Pedoman Teknik Dasar Untuk Laboratorium Kesehatan (Manual of Basic Techniques for A Health Laboratory). Buku Kedokteran-EGC: Jakarta.

Kementerian Kesehatan Indonesia. (2016). Profil Kesehatan Indonesia Tahun 2015.

Dinas Kesehatan Kabupaten Lombok Barat. (2016). Profil Kesehatan 2015.

Direktorat Jenderal Pengendalian Penyakit dan Penyehatan Lingkungan Departemen Kesehatan RI. (2011). Pedoman Teknis Pemeriksaan Parasit Malaria. Kementerian Kesehatan Republik Indonesia; 2011.

Purnomo, Rahmad A. (2010). Atlas Diagnostik Malaria. EGC: Jakarta.

Angchaisuksiri, Pantep. (2014). Coagulopathy in malaria. Thromb Res. 133(1):5–9. DOI: http://10.1016/j.thromres.2013.09.030

Mohapatra, S., Samantaray, J. C., Arulselvi, S., Ghosh, A. (2013). Disseminated intravascular coagulation following malaria due to Plasmodium vivax: A thromboelastography-based study. Malar J. 12(1):2–5. DOI: http://doi:10.1186/1475-2875-12-336

Adeayo, L.O., Adedire, A. O. (2012). Fibrinolytic Activities in Malaria Patients at the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, Nigeria. Res J Med Sci 6. 6(3):134–7. DOI: http://doi:10.4314/eamj.v82i2.9263

Kattula, S., Byrnes, J. R., Wolberg, A. S. (2017). Fibrinogen and fibrin in hemostasis and thrombosis. Arterioscler Thromb Vasc Biol. 37(3):13–21. DOI: http://doi:10.1161/ATVBAHA.117.308564

Weisel, John W & Litvinov, Rutem I. (2017). Fibrin Formation, Structure and Properties. Subcell Biochem. 82:405–56. DOI: http://doi:10.1007/978-3-319-49674-0_13

Kiswari, Rukman. (2014). Hematologi dan Transfusi. Erlangga: Jakarta.

Kementerian Kesehatan Indonesia. (2011). Pedoman Interpretasi Data Klinik.

Dewi, M. M. W., Herawati, S., Mulyantari, N. K., Prabawa, I. P. Y. (2019). The Comparison of Erythrocyte Sedimentation Rate ( ESR ) Modify Westergren Caretium Xc-A30 and Westergren Manual in Clinical Pathology Laboratory, Sanglah General Hospital, Denpasar, Bali. Bali Med J. 8(2):396–9. DOI: http://doi:10.15562/bmj.v8i2.1401

Notoatmodjo, Soekidjo. (2012). Metodologi Penelitian Kesehatan. Rineka Cipta: Jakarta.

Patil, Asha., Muduthan, Viviek R., Kunder, G. (2019). Can ESR be a diagnostic marker for assesing the severity of malaria infection? A retrospective study. Bangladesh Jour Med Sci. 18(04):756–9. DOI: http://doi:10.3329/bjms.v18i4.42881

Bochen, K., Krasowska, A., Milaniuk, S., Kulczyńska, M., Prystupa, A. (2011). Erythrocyte sedimentation rate – an old marker with new applications. J Pre-Clinical Clin Res. 5(2):50–5.

Harrison Michael. (2015). Erythrocyte sedimentation rate and C-reactive protein. Aust Prescr. 38(3):93–4. DOI: http://doi: 10.18773/austprescr.2015.034

Lindblade, K. A., Steinhardt, L., Samuels, A., Kachur, S. P., Lindblade, K. A., Steinhardt, L., et al. (2013). The silent threat : asymptomatic parasitemia and malaria transmission. Expert Rev Anti Infect Ther. 11(6). DOI: http://doi:10.1586/eri.13.45.

Wilairatana, Polrat., Tangpukdee, Noppadon., Krudsood, Srivicha. (2013). Definition of hyperparasitemia in severe falciparum malaria should be updated. Asian Pac J Trop Biomed. 3(7). DOI: http://doi:10.1016/S2221-1691(13)60119-7

Sorontou, Yohanna. (2013). Ilmu Malaria Klinik. Penerbit Buku Kedokteran EGC: Jakarta.

Nugraha, Gilang. (2015). Panduan Pemeriksaan Laboratorium Hematologi Dasar. Trans Info Media: Jakarta

Liswanti, Yane. (2014). Gambaran Laju Endap Darah (Metode Sedimant) Menggunakan Natrium Sitrat 3,8% dan EDTA yang di Tambah NaCl 0,85%. J Kesehat Bakti Tunas Husada. 12(1):226–35. DOI: http://doi:dx.doi.org/10.36465/jkbth.v12i1.83

Lapau, Buchari. (2013). Metode Penelitian Kesehatan. Pustaka Obor: Jakarta.

Published
2019-11-01
How to Cite
Kadeq Novita Prajawanti. (2019). Parasite density and erythrocyte sedimentation rate on patients with uncomplicated tropical malaria in two puskesmas of west Lombok. Medical Laboratory Analysis and Sciences Journal, 1(2), 9-15. https://doi.org/10.35584/melysa.v1i2.25